Urinary Citrate Levels Do Not Correlate with Urinary pH in Patients with Urinary Stone Formation
نویسندگان
چکیده
منابع مشابه
Urinary pH and stone formation.
The formation of various types of kidney stones is strongly influenced by urinary pH. An alkaline pH favors the crystallization of calcium- and phosphate-containing stones, whereas and acidic urine pH promotes uric acid or cystine stones. The activity of many transport processes involved in calcium, citrate and phosphate handling are sensitive to changes in systemic or local pH as shown for sev...
متن کاملStone clustering of patients with cystine urinary stone formation.
OBJECTIVES To explore the history of symptomatic cystine stone formation. Cystinuria is a genetic defect that may result in the formation of recurrent cystine calculi. METHODS Thirty-four patients with cystinuria were retrospectively evaluated for treatment patterns, medical prophylaxis, and renal outcome. Patients were offered a conservative surgical regimen and routine radiographic and labo...
متن کاملUrinary citrate in kidney stone disease.
BACKGROUND Hypocitraturia, or low urinary citrate excretion is known as a risk for nephrolithiasis. Though urinary citrate excretion is basically determined by acid-base balance, metabolic acidosis is not always manifest in urinary stone patients with hypocitraturia. From our stone clinic data, we estimated the incidence of hypocitraturia and addressed its causes in the absence of obvious acid-...
متن کاملModulators of urinary stone formation.
Urine contains compounds that modulate the nucleation, growth and aggregation of crystals as well as their attachment to renal epithelial cells. These compounds may function to protect the kidneys against: 1, the possibility of crystallization in tubular fluid and urine, which are generally metastable with respect to calcium salts, 2, crystal retention within the kidneys thereby preventing ston...
متن کاملDefective urinary crystallization inhibition and urinary stone formation.
INTRODUCTION Nephrocalcin (NC) is a glycoprotein produced in the kidney and inhibits calcium oxalate crystal formation. It has been separated into 4 isoforms (A, B, C, and D) and found that (A + B) are more abundant than (C + D) in urine of healthy subjects, but the reverse is seen in human urine of kidney stone patients. To further examine the role of this protein in inhibition of urinary crys...
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ژورنال
عنوان ژورنال: Urology
سال: 2007
ISSN: 0090-4295
DOI: 10.1016/j.urology.2007.04.052